Maternal and neonatal outcomes of pregnant women with COVID-19 pneumonia: a case-control study

Na Li; Lefei Han; Min Peng; Yuxia Lv; Yin Ouyang; Kui Liu; Linli Yue; Qiannan Li; Guoqiang Sun; Lin Chen; Lin Yang

The copyright holder for this preprint (which was not peer-reviewed) is . https://doi.org/10.1101/2020.03. 10.20033605 doi: medRxiv preprint To our best knowledge, this is the first case-control study to comprehensively compare maternal and neonatal outcomes of COVID-19 pneumonia with the patients with non-COVID-19 pneumonia and without pneumonia. We found that SARS-CoV-2 infection caused generally mild respiratory symptoms in pregnant women. Clinical signs and symptoms mainly included fever and pneumonia, but other respiratory symptoms were less common. Our results echo the findings of a previous study in pregnant women with SARS in Hong Kong, reporting that fever was the dominant presenting symptom [16] . However, it is of note that most patients did not have any symptoms on admission. For the purpose of screening for suspected cases, we asked all pre-laboring pregnant women to take low-dose chest CT scans with the abdominal region covered, and found that 2.1% fulfilled the criteria of COVID-19 pneumonia (patchy shadows and ground glass opacity in single or both lungs).