Author: Chong, Woon H.; Saha, Biplab K.; Conuel, Edward; Chopra, Amit
Title: The Incidence of Pleural Effusion in COVID-19 Pneumonia: State-of-the-Art Review Cord-id: syow6p4f Document date: 2021_2_27
ID: syow6p4f
Snippet: BACKGROUND: COVID-19-related pleural effusions are frequently described during the ongoing pandemic. OBJECTIVES: We described the incidence, characteristics, and outcomes of COVID-19-related pleural effusions based on the current evidence available in the literature. METHODS: We searched MEDLINE, Pubmed, and Google Scholar databases using keywords of “coronavirus disease 2019 (COVID-19),†“severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),†“pleural effusion,†“pleural f
Document: BACKGROUND: COVID-19-related pleural effusions are frequently described during the ongoing pandemic. OBJECTIVES: We described the incidence, characteristics, and outcomes of COVID-19-related pleural effusions based on the current evidence available in the literature. METHODS: We searched MEDLINE, Pubmed, and Google Scholar databases using keywords of “coronavirus disease 2019 (COVID-19),†“severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2),†“pleural effusion,†“pleural fluid,†and “pleura†from January 1(st), 2020 to January 31(st), 2021. RESULTS: The incidence of pleural effusions was low at 7.3% among the 47 observational studies. Pleural effusions were commonly observed in critically ill patients and had Multisystem Inflammatory Syndrome (MIS). COVID-19-related pleural effusions were identified 5-7 days and 11 days, after hospital admission and onset of COVD-19 symptoms. The characteristic findings of pleural fluid were exudative, lymphocytic or neutrophilic-predominant pleural fluid with markedly elevated lactate dehydrogenase (LDH) levels and pleural fluid to serum LDH ratio. CONCLUSION: A well-designed study is required to assess the significance of COVID-19-related pleural effusions during this current pandemic.
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