Selected article for: "death date recovery date and imputed onset date"
Author: Robert Verity; Lucy C Okell; Ilaria Dorigatti; Peter Winskill; Charles Whittaker; Natsuko Imai; Gina Cuomo-Dannenburg; Hayley Thompson; Patrick Walker; Han Fu; Amy Dighe; Jamie Griffin; Anne Cori; Marc Baguelin; Sangeeta Bhatia; Adhiratha Boonyasiri; Zulma M Cucunuba; Rich Fitzjohn; Katy A M Gaythorpe; Will Green; Arran Hamlet; Wes Hinsley; Daniel Laydon; Gemma Nedjati-Gilani; Steven Riley; Sabine van-Elsand; Erik Volz; Haowei Wang; Yuanrong Wang; Xiayoue Xi; Christl Donnelly; Azra Ghani; Neil Ferguson
Title: Estimates of the severity of COVID-19 disease
  • Document date: 2020_3_13
    • ID: 10n2u1b1_29
    Snippet: We used parametric (Supplementary Information) and non-parametric methods 11,25 to estimate the CFR in cases reported outside mainland China using individual-level data on dates of onset, date of report and date of outcome (death, recovery or unknown). Cases where the outcome was unknown were treated as censored observations. For 72% of cases, the date of onset was not reported. For the cases with known date of reporting and missing onset date (n.....
    Document: We used parametric (Supplementary Information) and non-parametric methods 11,25 to estimate the CFR in cases reported outside mainland China using individual-level data on dates of onset, date of report and date of outcome (death, recovery or unknown). Cases where the outcome was unknown were treated as censored observations. For 72% of cases, the date of onset was not reported. For the cases with known date of reporting and missing onset date (n=958) we imputed the date of onset from the observed onset-to-report times. Furthermore, 21% of reports of case recoveries mentioned this in aggregate (e.g. x recoveries on day y) and hence could not be linked to a specific case. This was accounted for in the fitting by including an additional parameter to estimate the proportion of recoveries reported. The parametric models were fitted to the data using Bayesian methods (see Supplementary Material). For the non-parametric method we randomly imputed the missing dates of onset and recovery status 100 times.

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