An assessment of the learning curve for EUS-guided gastroenterostomy for a single operator.

Jovani, Manol; Ichkhanian, Yervant; Parsa, Nasim; Singh, Sahiljeet; Brewer Gutierrez, Olaya I; Keane, Geri; Al Ghamdi, Sarah S; Ngamruengphong, Saowanee; Kumbhari, Vivek; Khashab, Mouen A

BACKGROUND AND AIMS Endoscopic ultrasound-guided gastroenterostomy (EUS-GE) is increasingly being used as an alternative to surgery and enteral stenting to manage gastric outlet obstruction (GOO). However, no data are available on the learning curve (LC) for EUS-GE. Defining it is necessary for the creation of adequate subspecialty training programs and quality assurance. METHODS This study is a retrospective analysis of a prospectively maintained dataset of patients that underwent EUS-GE at one tertiary referral center. Primary outcome was the LC for EUS-GE defined by the number of cases needed to achieve proficiency and mastery using cumulative sum (CUSUM) analysis. Moving average graphs and sequential time-block analysis were also performed to assess procedural time. Secondary outcomes included efficacy and safety of EUS-GE. RESULTS Eighty-seven consecutive patients underwent EUS-GE, mostly for malignant GOO. For consistency, 14 patients were excluded from analysis (noncautery-assisted EUS-GE 11, surgical anatomy 3). The same endoscopist performed all procedures using the same freehand technique. Technical success was achieved in 68 out of 73 (93%) patients. Immediate AEs occurred in 4 (5.5%) patients, whereas late AEs occurred only in 1 (1%) patient, all managed conservatively or endoscopically. All immediate adverse events occurred during the first 39 cases. Clinical success (defined as resuming at least oral liquid diet within a week) was achieved in 97% of patients. The mean procedural time was 36 minutes (SD 24). Evaluation of the CUSUM curve revealed that 25 cases were needed to achieve proficiency and 40 cases to achieve mastery. These results were confirmed with the average moving curve and sequential time-block analysis. CONCLUSION We report, for the first time, data on the learning curve for EUS-GE. About 25 procedures can be considered as the threshold to achieve proficiency and about 40 cases are needed to reach mastery of the technique.