Author: Cardonaâ€Hernandez, Roque; Cherubini, Valentino; Iafusco, Dario; Schiaffini, Riccardo; Luo, Xiaoping; Maahs, David M
Title: Children and youth with diabetes are not at increased risk for hospitalization due to COVIDâ€19 Cord-id: tq630a4f Document date: 2020_11_26
ID: tq630a4f
Snippet: The severe acute respiratory syndrome coronavirus 2 (SARSâ€Covâ€2), responsible for the coronavirus disease COVIDâ€19, was first identified in Wuhan, China in December 2019. Diabetes, as well as other cardiovascular comorbidities, has been recognized as a major risk factor for outcomes and mortality in adults with COVIDâ€19, particularly in the elderly with type 2 diabetes. Based on these conclusions, COVIDâ€19 data on adults have been generalized to youth with diabetes. Nevertheless, exper
Document: The severe acute respiratory syndrome coronavirus 2 (SARSâ€Covâ€2), responsible for the coronavirus disease COVIDâ€19, was first identified in Wuhan, China in December 2019. Diabetes, as well as other cardiovascular comorbidities, has been recognized as a major risk factor for outcomes and mortality in adults with COVIDâ€19, particularly in the elderly with type 2 diabetes. Based on these conclusions, COVIDâ€19 data on adults have been generalized to youth with diabetes. Nevertheless, experience from pediatric diabetes practices in China (Wuhan), Italy, Spain (Catalonia), and the United States (San Francisco Bay Area) consistently report only a single severe case of COVIDâ€19 in a 20â€yearâ€old female youth with type 1 diabetes (T1D) that was hospitalized for bilateral pneumonia and was subsequently discharged without complications. In Italy, information on COVIDâ€19 in all children with diabetes is collected on a weekly basis and those with positive swab test or infectionâ€related symptoms reported to a dedicated national registry. Of a total of 15 500 children tested, 11 subjects with T1D (age 8â€17y) tested positive for COVIDâ€19; 6/11 were asymptomatic and the rest presented with mild symptoms. In the rest of locations, youths with T1D diagnosed with COVIDâ€19 were based on clinical suspicion and a confirmatory PCR test (Wuhan:0; Cataloniaâ€HSJD:3; Californiaâ€Stanford:2). All of them were asymptomatic or had a mild course. We suggest that COVIDâ€19 data from adults should not be generalized to children, adolescents, and youth with diabetes as their outcomes and prognosis seem to be similar to their nonâ€diabeticâ€peers and consistently milder than adults with diabetes.
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