Author: Schachter, Julius; Chernesky, Max
Title: Alternate nucleic acid targets can be used to create a composite standard to evaluate clinical performance of nucleic acid amplification tests. Cord-id: y2lv21dy Document date: 2019_1_1
ID: y2lv21dy
Snippet: Evaluating the clinical performance of a new nucleic acid amplification test (NAAT) for Mycoplasma genitalium (MG), B. Kirkconnell et al. (J Clin Microbiol 57:e00264-19, 2019, https://doi.org/10.1128/JCM.00264-19) created 3 alternate NAATs that detected other unique MG gene targets. Lacking a reference standard, they used the consensus of results with those 3 NAATs as the comparator. This approach could be a new paradigm to evaluate new NAATs when there is no previously defined reference standar
Document: Evaluating the clinical performance of a new nucleic acid amplification test (NAAT) for Mycoplasma genitalium (MG), B. Kirkconnell et al. (J Clin Microbiol 57:e00264-19, 2019, https://doi.org/10.1128/JCM.00264-19) created 3 alternate NAATs that detected other unique MG gene targets. Lacking a reference standard, they used the consensus of results with those 3 NAATs as the comparator. This approach could be a new paradigm to evaluate new NAATs when there is no previously defined reference standard.
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