Author: Clark, Brandi L.; Thomas, Paul G.
Title: A Cell for the Ages: Human γδ T Cells across the Lifespan Cord-id: y7bnzv24 Document date: 2020_11_24
ID: y7bnzv24
Snippet: The complexity of the human immune system is exacerbated by age-related changes to immune cell functionality. Many of these age-related effects remain undescribed or driven by mechanisms that are poorly understood. γδ T cells, while considered an adaptive subset based on immunological ontogeny, retain both innate-like and adaptive-like characteristics. This T cell population is small but mighty, and has been implicated in both homeostatic and disease-induced immunity within tissues and through
Document: The complexity of the human immune system is exacerbated by age-related changes to immune cell functionality. Many of these age-related effects remain undescribed or driven by mechanisms that are poorly understood. γδ T cells, while considered an adaptive subset based on immunological ontogeny, retain both innate-like and adaptive-like characteristics. This T cell population is small but mighty, and has been implicated in both homeostatic and disease-induced immunity within tissues and throughout the periphery. In this review, we outline what is known about the effect of age on human peripheral γδ T cells, and call attention to areas of the field where further research is needed.
Search related documents:
Co phrase search for related documents- activation marker and adaptive immunity: 1, 2, 3, 4
- activation marker and adaptive immunity innate: 1
- activation status and adaptive immunity: 1, 2, 3, 4
- activation status and adaptive immunity innate: 1, 2
Co phrase search for related documents, hyperlinks ordered by date