A special case of COVID-19 with long duration of viral shedding for 49 days

Li Tan; Xia Kang; Bo Zhang; Shangen Zheng; Bo Liu; Tiantian Yu; Fan Yang; Qiongshu Wang; Hongming Miao

Besides to the long duration, several points should also be concerned. Firstly, the virus infecting this family cluster case appeared low toxicity and low transmissibility. However, it also showed a prolonged infective ability and was hardly to be eliminated in body. This virus type may exist in human bodies for a long time and may be a risk to contribute to periodic outbreak in future considering the high mutation in COVID-19. Secondly, a rapidly controlled fever with normal level of immune cells may be a good predictor to identify patients with superior outcomes in early stage. This conclusion is needed to be validated in carefully designed clinical studies. Thirdly, plasma infusion could be an efficient therapy for patients with COVID-19. Last, long term health status and the infective ability of these people are needed to be followed up due to prolonged infection. Our report provides valuable information for public health management and for the decision making in triage and long-term . CC-BY-NC-ND 4.0 International license It is made available under a is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. . CC-BY-NC-ND 4.0 International license It is made available under a is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. . CC-BY-NC-ND 4.0 International license It is made available under a is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. Moderate-cured, Moderate type of cases with a cured outcome; IL-6, interleukin-6; PCT, procalcitonin . CC-BY-NC-ND 4.0 International license It is made available under a is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity.