Author: Kwang Su Kim; Keisuke Ejima; Yusuke Ito; Shoya Iwanami; Hirofumi Ohashi; Yoshiki Koizumi; Yusuke Asai; Shinji Nakaoka; Koichi Watashi; Robin N Thompson; Shingo Iwami
Title: Modelling SARS-CoV-2 Dynamics: Implications for Therapy Document date: 2020_3_27
ID: 09r4d3nu_19
Snippet: However, if therapy is initiated after peak viral load (more than 2-3 days following 196 symptom onset), the effect on viral load AUC is limited. Compared with either 197 blocking de novo infection or virus production, promoting cytotoxicity showed 198 relatively mild effects on AUC reduction, however initiation of that therapy after the 199 peak viral load has the potential to still reduce viral load AUC (Fig. 3F) . 200.....
Document: However, if therapy is initiated after peak viral load (more than 2-3 days following 196 symptom onset), the effect on viral load AUC is limited. Compared with either 197 blocking de novo infection or virus production, promoting cytotoxicity showed 198 relatively mild effects on AUC reduction, however initiation of that therapy after the 199 peak viral load has the potential to still reduce viral load AUC (Fig. 3F) . 200
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