Author: Kwang Su Kim; Keisuke Ejima; Yusuke Ito; Shoya Iwanami; Hirofumi Ohashi; Yoshiki Koizumi; Yusuke Asai; Shinji Nakaoka; Koichi Watashi; Robin N Thompson; Shingo Iwami
Title: Modelling SARS-CoV-2 Dynamics: Implications for Therapy Document date: 2020_3_27
ID: 09r4d3nu_1
Snippet: We analysed data describing SARS-CoV-2 viral loads reported by Zou et al. 81 (1) and MERS-CoV viral loads reported by Oh et al. (8) using a simple mathematical 82 model (see Methods). To consider inter-individual variations in viral loads, a 83 nonlinear mixed-effect modelling approach was employed to estimate parameters 84 (see Methods). The estimated parameters and initial values are listed in Table 1 , 85 and the typical behaviour of the model.....
Document: We analysed data describing SARS-CoV-2 viral loads reported by Zou et al. 81 (1) and MERS-CoV viral loads reported by Oh et al. (8) using a simple mathematical 82 model (see Methods). To consider inter-individual variations in viral loads, a 83 nonlinear mixed-effect modelling approach was employed to estimate parameters 84 (see Methods). The estimated parameters and initial values are listed in Table 1 , 85 and the typical behaviour of the model using these best-fit parameter estimates is 86
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