Selected article for: "differential expression and RNA isolation"

Author: Cui, Lunbiao; Markou, Athina; Stratton, Charles W.; Lianidou, Evi
Title: Diagnosis and Assessment of Microbial Infections with Host and Microbial MicroRNA Profiles
  • Cord-id: hnky9u87
  • Document date: 2018_11_10
  • ID: hnky9u87
    Snippet: MicroRNAs (miRNAs) encoded by viral genome or host have been found participating in host-microbe interactions. Differential expression profiles of miRNAs were shown linking to specific disease pathologies which indicated its potency as diagnostic/prognostic biomarkers of infectious disease. This was emphasized by the discovery of circulating miRNAs which were found to be remarkably stable in mammalian biofluids. Standardized methods of miRNA quantification including RNA isolation should be estab
    Document: MicroRNAs (miRNAs) encoded by viral genome or host have been found participating in host-microbe interactions. Differential expression profiles of miRNAs were shown linking to specific disease pathologies which indicated its potency as diagnostic/prognostic biomarkers of infectious disease. This was emphasized by the discovery of circulating miRNAs which were found to be remarkably stable in mammalian biofluids. Standardized methods of miRNA quantification including RNA isolation should be established before they will be ready for use in clinical practice.

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