Selected article for: "admission duration and lung function"
Author: McGroder, Claire F; Zhang, David; Choudhury, Mohammad A; Salvatore, Mary M; D'Souza, Belinda M; Hoffman, Eric A; Wei, Ying; Baldwin, Matthew R; Garcia, Christine Kim
Title: Pulmonary fibrosis 4 months after COVID-19 is associated with severity of illness and blood leucocyte telomere length
  • Cord-id: xeqonl13
  • Document date: 2021_4_29
    • ID: xeqonl13
    Snippet: The risk factors for development of fibrotic-like radiographic abnormalities after severe COVID-19 are incompletely described and the extent to which CT findings correlate with symptoms and physical function after hospitalisation remains unclear. At 4 months after hospitalisation, fibrotic-like patterns were more common in those who underwent mechanical ventilation (72%) than in those who did not (20%). We demonstrate that severity of initial illness, duration of mechanical ventilation, lactate
    Document: The risk factors for development of fibrotic-like radiographic abnormalities after severe COVID-19 are incompletely described and the extent to which CT findings correlate with symptoms and physical function after hospitalisation remains unclear. At 4 months after hospitalisation, fibrotic-like patterns were more common in those who underwent mechanical ventilation (72%) than in those who did not (20%). We demonstrate that severity of initial illness, duration of mechanical ventilation, lactate dehydrogenase on admission and leucocyte telomere length are independent risk factors for fibrotic-like radiographic abnormalities. These fibrotic-like changes correlate with lung function, cough and measures of frailty, but not with dyspnoea.

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