Author: Smita Gopinath; Myoungjoo V. Kim; Tasfia Rakib; Patrick W. Wong; Michael van Zandt; Natasha A. Barry; Tsuneyasu Kaisho; Andrew L. Goodman; Akiko Iwasaki
Title: Microbiota-independent antiviral protection conferred by aminoglycoside antibiotics Document date: 2018_1_16
ID: dzorkks5_11
Snippet: Neomycin is a member of a large and diverse group of aminoglycosides, many of which 139 are commonly used to treat bacterial infection. To determine if ISG induction was common 140 across the aminoglycoside family, we treated mice with a panel of structurally diverse 141 aminoglycosides for 1-2 days. Five out of the seven aminoglycosides we tested 142 significantly increased ISG expression upon application to the vaginal mucosa (Fig. 2d) . 143 au.....
Document: Neomycin is a member of a large and diverse group of aminoglycosides, many of which 139 are commonly used to treat bacterial infection. To determine if ISG induction was common 140 across the aminoglycoside family, we treated mice with a panel of structurally diverse 141 aminoglycosides for 1-2 days. Five out of the seven aminoglycosides we tested 142 significantly increased ISG expression upon application to the vaginal mucosa (Fig. 2d) . 143 author/funder. All rights reserved. No reuse allowed without permission.
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