Selected article for: "amino acid and cov sequence"
Author: Maria Bzówka; Karolina Mitusinska; Agata Raczynska; Aleksandra Samol; Jack Tuszynski; Artur Góra
Title: Molecular Dynamics Simulations Indicate the SARS-CoV-2 Mpro Is Not a Viable Target for Small-Molecule Inhibitors Design
  • Document date: 2020_3_2
    • ID: mp3a9c9u_41
    Snippet: SARS-CoV Mpro was downloaded from the PDB (PDB ID: 1q2w). Blast [57] was run based on the amino acid sequence. As a result, 2643 sequences of viral main proteases similar to chain A SARS-CoV Mpro were obtained. Clustal Omega [58] was used to prepare an alignment of those sequences. Comulator was then employed to calculate the correlation between amino acids and based on the results, groups of positions in SARS-CoV Mpro sequence were selected whos.....
    Document: SARS-CoV Mpro was downloaded from the PDB (PDB ID: 1q2w). Blast [57] was run based on the amino acid sequence. As a result, 2643 sequences of viral main proteases similar to chain A SARS-CoV Mpro were obtained. Clustal Omega [58] was used to prepare an alignment of those sequences. Comulator was then employed to calculate the correlation between amino acids and based on the results, groups of positions in SARS-CoV Mpro sequence were selected whose amino acid occurrences strongly depended on each other.

    Search related documents:
    Co phrase search for related documents
    • amino acid sequence and main protease: 1, 2
    • amino acid sequence and Mpro sequence: 1
    • amino acid sequence and SARS CoV Mpro sequence: 1
    • amino acid sequence and sequence alignment: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51
    • main protease and Mpro sequence: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
    • main protease and SARS CoV Mpro sequence: 1, 2, 3, 4, 5
    • main protease and sequence alignment: 1, 2, 3
    • Mpro sequence and SARS CoV Mpro sequence: 1, 2, 3, 4, 5, 6, 7
    • Mpro sequence and sequence alignment: 1
    • sequence alignment and strongly depend: 1