Author: MJ Morwitzer; A Corona; L Zinzula; E Fanunza; C Nigri; S Distinto; C Vornholt; V Kumar; E Tramontano; SP Reid
Title: Mutation of Ebola virus VP35 Ser129 uncouples interferon antagonist and replication functions Document date: 2019_8_7
ID: cbyzdnrp_72
Snippet: comparable to that of the non-stimulated vector control ( Figure 4C) . Collectively, the data show 459 that VP35-S129A retains IFN antagonist activity, indicating that VP35 Ser129 does not impact 460 IFN antagonist function. 461 VP35-S129A abrogates EBOV minigenome activity and interaction with L 1-505 462.....
Document: comparable to that of the non-stimulated vector control ( Figure 4C) . Collectively, the data show 459 that VP35-S129A retains IFN antagonist activity, indicating that VP35 Ser129 does not impact 460 IFN antagonist function. 461 VP35-S129A abrogates EBOV minigenome activity and interaction with L 1-505 462
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