Author: Bozzali, Marco; Grassini, Alberto; Morana, Giovanni; Zotta, Michela; Cabras, Sara; Romagnolo, Alberto; Artusi, Carlo Alberto; Montalenti, Elisa; Rizzone, Mario Giorgio; Garbossa, Diego; Montanaro, Elisa; Cercignani, Mara; Lopiano, Leonardo
Title: Focal seizures with impaired awareness as long-term neurological complication of COVID-19: a case report Cord-id: jpu2tgjz Document date: 2021_4_16
ID: jpu2tgjz
Snippet: We report here the first case of a young individual otherwise healthy, who presented with frequent focal seizures with impaired awareness as a possible long-term complication of severe acute respiratory syndrome coronavirus-2 infection. Seizures were documented by electroencephalography and responded clinically and neuro-physiologically to antiseizure therapy. The patient underwent an extensive investigation including cerebrospinal fluid examination, conventional and quantitative brain magnetic
Document: We report here the first case of a young individual otherwise healthy, who presented with frequent focal seizures with impaired awareness as a possible long-term complication of severe acute respiratory syndrome coronavirus-2 infection. Seizures were documented by electroencephalography and responded clinically and neuro-physiologically to antiseizure therapy. The patient underwent an extensive investigation including cerebrospinal fluid examination, conventional and quantitative brain magnetic resonance imaging, and 18-FDG positron emission tomography. Beyond the clinical interest, this case contributes to clarify the possible pathways by which SARS-CoV-2 may enter the central nervous system and cause long-term neurological complications.
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