Author: Bhuiyan, A. T.; Nath, S. D.; Das, S.; Das, M.; Biswas, R.; Ahsan, M.; Ziad, M. I.-E.-A.; Padma, F. K.; Dey, R.; Alam, A. S.; Zehan, F. H.; Saha, A.
Title: Clinical observation of high-flow nasal cannula (HFNC) with non-rebreather mask (NRM) use on severe or critically ill COVID-19 diabetic patients Cord-id: zs2a8pd9 Document date: 2021_10_18
ID: zs2a8pd9
Snippet: Objective: Diabetes prevalence is a vital factor in COVID-19's clinical prognosis. This study aimed to investigate and compare the efficacy of High-flow Nasal Cannula (HFNC) with/without non-rebreather mask (NRM) on critical COVID-19 patients with/without diabetes. Materials and methods: For analysis and comparison, epidemiological, biochemical, and clinical data were collected from 240 HFNC{+/-}NRM treated severe and critical COVID-19 ICU patients (diabetic = 136; non-diabetic = 104) of five ho
Document: Objective: Diabetes prevalence is a vital factor in COVID-19's clinical prognosis. This study aimed to investigate and compare the efficacy of High-flow Nasal Cannula (HFNC) with/without non-rebreather mask (NRM) on critical COVID-19 patients with/without diabetes. Materials and methods: For analysis and comparison, epidemiological, biochemical, and clinical data were collected from 240 HFNC{+/-}NRM treated severe and critical COVID-19 ICU patients (diabetic = 136; non-diabetic = 104) of five hospitals in Chattogram, Bangladesh. Results and Discussion: 59.1% patients with fever had diabetes (p=0.012). ICU stay was longer for diabetic patients (9.06{+/-}5.70) than non-diabetic ones (7.41{+/-}5.11) (p=0.020). Majority of hypertensive patients were diabetic (68.3%; p<0.001). Most of the diabetic patients (70.4%; p<0.005) had elevated creatinine levels. The partial pressure of oxygen after HFNC (only) was significantly (p=0.031) higher in non-diabetic patients (69.30{+/-}23.56) than diabetic ones (61.50{+/-}14.49). Diabetic (62.64{+/-}13.05) and non-diabetic patients (59.40{+/-}13.22) had similar partial pressure of oxygen from HFNC+NRM. Majority of the diabetic patients who required HFNC+NRM had elevated RBS (73.8%; p=0.001) and creatinine (75.7%; p=0.009). Factors affecting the HFNC only treated patients were fever and impaired glucose tolerance. Besides, increased plasma glucose level, age, and hypertension affected the HFNC + NRM treated diabetic patients. Conclusion: The results of this study imply that oxygen supply with HFNC+NRM may be beneficial for the elderly/hypertensive diabetic patients with COVID-19 associated AHRF; and that IGT and increased blood glucose levels could be determinants for COVID-19 severity. However, further experiments to substantiate these claims are required on a larger sample and among different clinical cohorts.
Search related documents:
Co phrase search for related documents- acute aki kidney injury and adjusted odd ratio: 1, 2
- acute aki kidney injury and logistic regression: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- acute aki kidney injury and long period: 1, 2
- acute aki kidney injury and long term effect: 1
- acute aki kidney injury and long term sequelae: 1
- acute aki kidney injury and low molecular weight heparin: 1, 2, 3, 4, 5
- acute ards respiratory distress syndrome and adjusted odd ratio: 1
- acute ards respiratory distress syndrome and logistic regression: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- acute ards respiratory distress syndrome and long period: 1, 2
- acute ards respiratory distress syndrome and long term effect: 1
- acute ards respiratory distress syndrome and long term sequelae: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10
- acute ards respiratory distress syndrome and low molecular weight heparin: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
- acute respiratory and adjusted odd ratio: 1, 2, 3, 4, 5
- acute respiratory and logistic regression: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- acute respiratory and long period: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- acute respiratory and long term effect: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
- acute respiratory and long term sequelae: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- acute respiratory and low molecular weight heparin: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- adjusted odd ratio and logistic regression: 1, 2, 3, 4, 5
Co phrase search for related documents, hyperlinks ordered by date