Selected article for: "important role and recent study"
Author: Pizuorno, Antonio; Brim, Hassan; Ashktorab, Hassan
Title: Gastrointestinal manifestations and SARS-CoV-2 infection
  • Cord-id: 0glsp26e
  • Document date: 2021_9_25
    • ID: 0glsp26e
    Snippet: Since COVID-19 occurrence in late 2019, intense research efforts on an unprecedented scale have focused on the study of SARS CoV-2 entry mechanisms and clinical presentations. As for other coronaviruses, SARS-CoV-2 presents with extra-respiratory clinical manifestations like diarrhea, nausea, vomiting and abdominal pain which highlight that the gastrointestinal (GI) system as another viral target along with the typical presentations of COVID-19 which is characterized primarily by respiratory sym
    Document: Since COVID-19 occurrence in late 2019, intense research efforts on an unprecedented scale have focused on the study of SARS CoV-2 entry mechanisms and clinical presentations. As for other coronaviruses, SARS-CoV-2 presents with extra-respiratory clinical manifestations like diarrhea, nausea, vomiting and abdominal pain which highlight that the gastrointestinal (GI) system as another viral target along with the typical presentations of COVID-19 which is characterized primarily by respiratory symptoms. The digestive system is involved in many systemic functions through the gut-brain-axis and systemic immunity modulation. Therefore, the GI system plays an important role in the presentation of the disease, pathogenesis, and possibly treatment outcome. This mini-review summarizes recent work to study SARS-CoV-2 infection as it relates to comorbidities, GI symptoms. This will help to strategize the priorities in understanding the impact of the virus on outcome in various aspects.

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