Author: Matt Williams; Kerlann Le Calvez; Ella Mi; Jiarong Chen; Seema Dadhania; Lillie Pakzad-Shahabi
Title: Estimating the Risks from COVID-19 Infection in Adult Chemotherapy Patients Document date: 2020_3_20
ID: mlwrfkm4_17
Snippet: Our model provides two estimates of risk in order to inform decisions. This model is based on the best available data, but is imperfect. We hope that better models will soon be available, but in the meantime oncologists need to make decisions about chemotherapy. Our model only requires oncologists to be able to specify the absolute improvement in overall survival, and then balance that against the predicted risk if the patient becomes COVID-19 in.....
Document: Our model provides two estimates of risk in order to inform decisions. This model is based on the best available data, but is imperfect. We hope that better models will soon be available, but in the meantime oncologists need to make decisions about chemotherapy. Our model only requires oncologists to be able to specify the absolute improvement in overall survival, and then balance that against the predicted risk if the patient becomes COVID-19 infected. Most older adult patients with solid tumours have a level of elevated risk such that, even if we assume lower rates of infection and case fatality rates, the harms are likely to outweigh the benefits for most chemotherapy in most patients. The uncertainty about whether increased risk is due to having . CC-BY-NC-ND 4.0 International license It is made available under a author/funder, who has granted medRxiv a license to display the preprint in perpetuity.
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