Selected article for: "cytotoxic concentration and selectivity index"
Author: Norio Yamamoto; Shutoku Matsuyama; Tyuji Hoshino; Naoki Yamamoto
Title: Nelfinavir inhibits replication of severe acute respiratory syndrome coronavirus 2 in vitro.
  • Document date: 2020_4_8
    • ID: 662pfa61_5
    Snippet: For the evaluation of the nine HIV-1 protease inhibitors, the 50% effective concentration (EC 50 ), the 50% cytotoxic concentration (CC 50 ), and the selectivity index (SI, CC 50 /EC 50 ) were analyzed. Moreover, based on the mean peak and trough serum concentration (C max and C trough ) of the compounds in human, C max -EC 50 ratio (C max /EC 50 ) and C trough -EC 50 ratio (C trough /EC 50 ) were calculated to assess the safety and efficacy of t.....
    Document: For the evaluation of the nine HIV-1 protease inhibitors, the 50% effective concentration (EC 50 ), the 50% cytotoxic concentration (CC 50 ), and the selectivity index (SI, CC 50 /EC 50 ) were analyzed. Moreover, based on the mean peak and trough serum concentration (C max and C trough ) of the compounds in human, C max -EC 50 ratio (C max /EC 50 ) and C trough -EC 50 ratio (C trough /EC 50 ) were calculated to assess the safety and efficacy of these compounds.

    Search related documents:
    Co phrase search for related documents
    • cytotoxic concentration and effective concentration: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • cytotoxic concentration and human compound: 1
    • cytotoxic concentration and selectivity index: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17
    • cytotoxic concentration and serum concentration: 1, 2, 3
    • cytotoxic concentration and SI selectivity index: 1, 2, 3, 4, 5, 6, 7, 8, 9
    • effective concentration and efficacy safety: 1, 2, 3, 4, 5
    • effective concentration and human compound: 1
    • effective concentration and protease inhibitor: 1, 2, 3
    • effective concentration and selectivity index: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20
    • effective concentration and serum concentration: 1, 2, 3, 4, 5
    • effective concentration and SI selectivity index: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
    • efficacy safety and human compound: 1
    • efficacy safety and protease inhibitor: 1, 2, 3, 4, 5, 6, 7, 8, 9
    • efficacy safety and selectivity index: 1, 2
    • efficacy safety and serum concentration: 1, 2, 3
    • efficacy safety and trough peak: 1
    • human compound and selectivity index: 1, 2
    • human compound and SI selectivity index: 1
    • protease inhibitor and selectivity index: 1, 2, 3