Author: James T. VanLeuven; Benjamin J. Ridenhour; Craig R. Miller; Tanya A. Miura
Title: Lung epithelial cells have virus-specific and shared gene expression responses to infection by diverse respiratory viruses Document date: 2016_12_2
ID: iedh762s_37
Snippet: There was strong overlap between the IFN-induced genes up-regulated by each virus. The timing of 245 IFN-related gene expression followed the same trend as was seen in Figure 1 . They further showed that these differences were mediated by differential signaling 290 through the IFN ï¡/ï¢ receptor, with robust signaling in uninfected cells. This supports our findings that PR8 291 induces expression of Ifnar2 and additional type I IFN genes that a.....
Document: There was strong overlap between the IFN-induced genes up-regulated by each virus. The timing of 245 IFN-related gene expression followed the same trend as was seen in Figure 1 . They further showed that these differences were mediated by differential signaling 290 through the IFN ï¡/ï¢ receptor, with robust signaling in uninfected cells. This supports our findings that PR8 291 induces expression of Ifnar2 and additional type I IFN genes that are not up-regulated by RV ( Figure 5 ).
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