Author: Yadi Zhou; Yuan Hou; Jiayu Shen; Yin Huang; William Martin; Feixiong Cheng
Title: Network-based Drug Repurposing for Human Coronavirus Document date: 2020_2_5
ID: b4mdiont_88
Snippet: is the (which was not peer-reviewed) The copyright holder for this preprint . https://doi.org/10.1101/2020.02.03.20020263 doi: medRxiv preprint where 〈 • 〉 was calculated based on the "closest" method. Our key methodology is that a drug combination is therapeutically effective only if it follows a specific relationship to the disease module, as captured by Complementary Exposure patterns in targets' modules of both drugs without overlapping.....
Document: is the (which was not peer-reviewed) The copyright holder for this preprint . https://doi.org/10.1101/2020.02.03.20020263 doi: medRxiv preprint where 〈 • 〉 was calculated based on the "closest" method. Our key methodology is that a drug combination is therapeutically effective only if it follows a specific relationship to the disease module, as captured by Complementary Exposure patterns in targets' modules of both drugs without overlapping toxic mechanisms. [25]
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