Author: Sellers, Subhashini A.; Dover, Kenton L.; Bailey, Aubrey G.; Cheves, Avery; Eason, Anthony B.; Popowitch, Elena B.; Miller, Melissa B.; Wohl, David A.; Dittmer, Dirk P.; Fischer, William A.
Title: Burden of respiratory viral infection in persons with human immunodeficiency virus Cord-id: k1g2mp3s Document date: 2020_3_9
ID: k1g2mp3s
Snippet: This study was conducted to determine the prevalence of respiratory viral infections (RVI) in persons living with HIV (PLH) admitted with a respiratory complaint using realâ€time reverse transcription polymerase chain reaction and primerâ€independent nextâ€generation sequencing (NGS). Of 82 subjects, respiratory viruses were the most common pathogen identified in 27 (33%), followed by fungus and bacteria in 8 (10%) and 4 (5%) subjects, respectively. Among subjects with RVI, 11 (41%) required
Document: This study was conducted to determine the prevalence of respiratory viral infections (RVI) in persons living with HIV (PLH) admitted with a respiratory complaint using realâ€time reverse transcription polymerase chain reaction and primerâ€independent nextâ€generation sequencing (NGS). Of 82 subjects, respiratory viruses were the most common pathogen identified in 27 (33%), followed by fungus and bacteria in 8 (10%) and 4 (5%) subjects, respectively. Among subjects with RVI, 11 (41%) required ICU admission and 16 (59%) required mechanical ventilation. The proportion of respiratory viruses identified, and the associated complicated hospital course highlights the significant role that RVIs play in the lung health of PLH.
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