How Could POCT be a Useful Tool for Migrant and Refugee Health?

Bernardini, Sergio; Pieri, Massimo; Ciotti, Marco

Point of care testing (POCT) represents an important step forward in the clinical management of patients. POC assays are easy to use and do not require skilled personnel; therefore they are particularly useful in low resource settings where diagnostics laboratories equipped with complex instruments that require well trained technicians are not available. Samples can be processed immediately overcoming the problems related to the stability of the sample, storage and shipping to a centralized laboratory hospital based. Furthermore, results are delivered in real-time, usually less than 1 hr; thus, a clinical decision can be taken earlier. A prompt diagnosis is crucial in the case of contagious diseases allowing a rapid isolation of the infected patient and treatment; thus, reducing the risk of transmission of the pathogen. In this report, we address the use of POC assays in the diagnosis of infectious pathogens including hepatitis B and C viruses, human immunodeficiency virus-type 1, human papillomavirus, chlamydia trachomatis, neisseria gonorrhea, trichomonas vaginalis, mycobacterium tuberculosis and the parasite plasmodium. These pathogens are commonly detected among vulnerable people such as refugees and migrants. The described POC assays are based on nuclei acid amplification technology (NAAT) that is generally characterized by a high sensitivity and specificity.