Selected article for: "Influenza virus and RNA virus"
Author: MJ Morwitzer; A Corona; L Zinzula; E Fanunza; C Nigri; S Distinto; C Vornholt; V Kumar; E Tramontano; SP Reid
Title: Mutation of Ebola virus VP35 Ser129 uncouples interferon antagonist and replication functions
  • Document date: 2019_8_7
    • ID: cbyzdnrp_70
    Snippet: were stimulated with influenza A virus (IAV)-RNA. After 24 h, reporter activity was measured to 446 assess IFN inhibition. IFN-β promoter activation was significantly inhibited by both VP35-WT 447 and VP35-S129A at comparable efficiencies ( Figure 4A ). Next, we tested the effect of VP35-WT 448.....
    Document: were stimulated with influenza A virus (IAV)-RNA. After 24 h, reporter activity was measured to 446 assess IFN inhibition. IFN-β promoter activation was significantly inhibited by both VP35-WT 447 and VP35-S129A at comparable efficiencies ( Figure 4A ). Next, we tested the effect of VP35-WT 448

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