Author: Yang, Bo; Zhang, Xiaohui; Zhang, Dajun; Hou, Jing; Xu, GuoWei; Sheng, Chaochao; Choudhury, Sk Mohiuddin; Zhu, Zixiang; Li, Dan; Zhang, Keshan; Zheng, Haixue; Liu, Xiangtao
Title: Molecular Mechanisms of Immune Escape for Foot-and-Mouth Disease Virus Cord-id: kczj24se Document date: 2020_9_4
ID: kczj24se
Snippet: Foot-and-mouth disease virus (FMDV) causes a highly contagious vesicular disease in cloven-hoofed livestock that results in severe consequences for international trade, posing a great economic threat to agriculture. The FMDV infection antagonizes the host immune responses via different signaling pathways to achieve immune escape. Strategies to escape the cell immune system are key to effective infection and pathogenesis. This review is focused on summarizing the recent advances to understand how
Document: Foot-and-mouth disease virus (FMDV) causes a highly contagious vesicular disease in cloven-hoofed livestock that results in severe consequences for international trade, posing a great economic threat to agriculture. The FMDV infection antagonizes the host immune responses via different signaling pathways to achieve immune escape. Strategies to escape the cell immune system are key to effective infection and pathogenesis. This review is focused on summarizing the recent advances to understand how the proteins encoded by FMDV antagonize the host innate and adaptive immune responses.
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