Author: Védy, Dana; Robert, Daniel; Gasparini, Danielle; Canellini, Giorgia; Waldvogel, Sophie; Tissot, Jean-Daniel
Title: Bacterial contamination of platelet concentrates: pathogen detection and inactivation methods Cord-id: 8hidjppo Document date: 2009_4_16
ID: 8hidjppo
Snippet: Whereas the reduction of transfusion related viral transmission has been a priority during the last decade, bacterial infection transmitted by transfusion still remains associated to a high morbidity and mortality, and constitutes the most frequent infectious risk of transfusion. This problem especially concerns platelet concentrates because of their favorable bacterial growth conditions. This review gives an overview of platelet transfusion-related bacterial contamination as well as on the diff
Document: Whereas the reduction of transfusion related viral transmission has been a priority during the last decade, bacterial infection transmitted by transfusion still remains associated to a high morbidity and mortality, and constitutes the most frequent infectious risk of transfusion. This problem especially concerns platelet concentrates because of their favorable bacterial growth conditions. This review gives an overview of platelet transfusion-related bacterial contamination as well as on the different strategies to reduce this problem by using either bacterial detection or inactivation methods.
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