Author: Meytal Galilee; Akram Alian
Title: Multimerization of HIV-1 integrase hinges on conserved SH3-docking platforms Document date: 2018_4_16
ID: 4fuxbte0_12
Snippet: Competency of peptide-bound IN for 3'processing activity indicates that peptide binding did not restrict the catalytic loop flexibility (density map is missing for residues 140-147) nor induced inactivating conformational changes to the enzyme (root-men-square deviation [RMSD] 0.30 Ã… to apo, PDB code: 1BIS)......
Document: Competency of peptide-bound IN for 3'processing activity indicates that peptide binding did not restrict the catalytic loop flexibility (density map is missing for residues 140-147) nor induced inactivating conformational changes to the enzyme (root-men-square deviation [RMSD] 0.30 Ã… to apo, PDB code: 1BIS).
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