Author: Min, Yuan-Qin; Huang, Mengzhuo; Sun, Xiulian; Deng, Fei; Wang, Hualin; Ning, Yun-Jia
Title: Immune evasion of SARS-CoV-2 from interferon antiviral system Cord-id: bggfy0j2 Document date: 2021_7_26
ID: bggfy0j2
Snippet: The on-going pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to unprecedented medical and socioeconomic crises. Although the viral pathogenesis remains elusive, deficiency of effective antiviral interferon (IFN) responses upon SARS-CoV-2 infection has been recognized as a hallmark of COVID-19 contributing to the disease pathology and progress. Recently, multiple proteins encoded by SARS-CoV-2 have been shown to act as
Document: The on-going pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to unprecedented medical and socioeconomic crises. Although the viral pathogenesis remains elusive, deficiency of effective antiviral interferon (IFN) responses upon SARS-CoV-2 infection has been recognized as a hallmark of COVID-19 contributing to the disease pathology and progress. Recently, multiple proteins encoded by SARS-CoV-2 have been shown to act as potential IFN antagonists with diverse possible mechanisms. Here, we summarize and discuss the strategies of SARS-CoV-2 for evasion of innate immunity (particularly the antiviral IFN responses), understanding of which will facilitate not only the elucidation of SARS-CoV-2 infection and pathogenesis but also the development of antiviral intervention therapies.
Search related documents:
Co phrase search for related documents- acid inducible and activity exhibit: 1
- acid inducible and adaptive immunity: 1, 2
- acid inducible gene and activate transcription factor: 1
- acid inducible gene and activity exhibit: 1
- acid inducible gene and adaptive immunity: 1, 2
- activity exhibit and adaptive immunity: 1
Co phrase search for related documents, hyperlinks ordered by date