Selected article for: "AUC curve and calibration curve"
Author: Xia, Yan; Zhang, Yan; Yuan, Shijin; Chen, Jiangnan; Zheng, Wei; Xu, Xiaoping; Xie, Xinyou; Zhang, Jun
Title: A nomogram to early predict isolation length for non-severe COVID-19 patients based on laboratory investigation: A multicenter retrospective study in Zhejiang Province, China
  • Cord-id: krsgaft4
  • Document date: 2020_12_3
    • ID: krsgaft4
    Snippet: BACKGROUND: Majority coronavirus disease 2019 (COVID-19) patients are classified as mild and moderate (non-severe) diseases. We aim to develop a model to predict isolation length for non-severe patients. METHODS: Among 188 non-severe patients, 96 patients were enrolled as training cohort to identify factors associated with isolation length via Cox regression model and develop a nomogram. Other 92 patients formed as validation cohort to validate nomogram. Concordance index (C-index), area under t
    Document: BACKGROUND: Majority coronavirus disease 2019 (COVID-19) patients are classified as mild and moderate (non-severe) diseases. We aim to develop a model to predict isolation length for non-severe patients. METHODS: Among 188 non-severe patients, 96 patients were enrolled as training cohort to identify factors associated with isolation length via Cox regression model and develop a nomogram. Other 92 patients formed as validation cohort to validate nomogram. Concordance index (C-index), area under the curve (AUC) and calibration curves were used to evaluated nomogram. RESULTS: Increasing absolute eosinophil count (AEC) after admission was correlated with shorter isolation length (P = 0.02). Baseline activated partial thromboplastin time (APTT) > 30 s was correlated with longer isolation length (P = 0.03). A nomogram to predict isolation probability at 11-, 16- and 21-day was developed and validated. The C-indices of training and validation cohort were 0.604 and 0.682 respectively. Both cohorts showed a good discriminative ability (AUC, 11-day: 0.646 vs 0.730; 16-day: 0.663 vs 0.750; 21-day: 0.711 vs 0.783; respectively) and calibration power. CONCLUSIONS: Baseline APTT and dynamic change of AEC were two significant factors associated with isolation length of non-severe patients. Nomogram could predict isolation probability for each patient to estimate appropriate quarantine length.

    Search related documents:
    Co phrase search for related documents
    • absolute lymphocyte count alc and acute respiratory syndrome coronavirus: 1, 2, 3, 4, 5, 6
    • absolute lymphocyte count alc and acute sars cov respiratory syndrome coronavirus: 1, 2, 3, 4, 5
    • absolute lymphocyte count and accurate prediction: 1
    • absolute lymphocyte count and acute respiratory syndrome coronavirus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15
    • absolute lymphocyte count and acute sars cov respiratory syndrome coronavirus: 1, 2, 3, 4, 5, 6, 7, 8, 9
    • absolute lymphocyte count and admission day: 1, 2, 3
    • absolute monocyte count amc and acute respiratory syndrome coronavirus: 1
    • absolute monocyte count amc and acute sars cov respiratory syndrome coronavirus: 1
    • absolute monocyte count and acute respiratory syndrome coronavirus: 1
    • absolute monocyte count and acute sars cov respiratory syndrome coronavirus: 1
    • absolute neutrophil count anc and acute respiratory syndrome coronavirus: 1
    • absolute neutrophil count anc and acute sars cov respiratory syndrome coronavirus: 1
    • absolute neutrophil count and acute respiratory syndrome coronavirus: 1, 2, 3, 4, 5, 6, 7
    • absolute neutrophil count and acute sars cov respiratory syndrome coronavirus: 1, 2, 3, 4, 5, 6
    • accurate prediction and actual result: 1
    • accurate prediction and acute respiratory syndrome coronavirus: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11
    • accurate prediction and acute sars cov respiratory syndrome coronavirus: 1, 2, 3, 4, 5, 6, 7, 8, 9
    • acute respiratory syndrome coronavirus and admission day: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • acute sars cov respiratory syndrome coronavirus and admission day: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25