Author: Kenichiro Sato; Tatsuo Mano; Atsushi Iwata; Tatsushi Toda
Title: Neuropsychiatric adverse events of chloroquine: A real-world pharmacovigilance study using the FAERS database Document date: 2020_4_14
ID: buzj06i6_2
Snippet: While chloroquine has a long history in the treatment of malaria and autoimmune diseases, its safety and efficacy in the treatment of COVID-19 remain unknown [5] . In the treatment of malaria and autoimmune diseases, chloroquine can cause numerous side effects such as nausea, headache, pruritus, worsening of psoriasis, retinopathy, and cardiac dysfunction. While neuropsychiatric symptoms such as seizure, coma, and psychosis, were also reported in.....
Document: While chloroquine has a long history in the treatment of malaria and autoimmune diseases, its safety and efficacy in the treatment of COVID-19 remain unknown [5] . In the treatment of malaria and autoimmune diseases, chloroquine can cause numerous side effects such as nausea, headache, pruritus, worsening of psoriasis, retinopathy, and cardiac dysfunction. While neuropsychiatric symptoms such as seizure, coma, and psychosis, were also reported in patients who received chloroquine [6, 7] , it is still unknown which neuropsychiatric symptoms are directly associated with the use of chloroquine, partly because of their relatively low frequency [8] . Understanding in advance the types of neuropsychiatric symptoms that may occur in patients treated with chloroquine, may be useful, particularly in patients with COVID-19 in intensive care units, where rapid clinical judgement is required.
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