Author: Myra Hosmillo; Jia Lu; Michael R. McAllaster; James B. Eaglesham; Xinjie Wang; Edward Emmott; Patricia Domingues; Yasmin Chaudhry; Timothy J Fitzmaurice; Matthew K.H. Tung; Marc Panas; Gerald McInerney; Nicholas Locker; Craig B. Willen; Ian Goodfellow
Title: Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation Document date: 2019_3_8
ID: d0q5lhf4_15
Snippet: VPg-linked RNA, and RNA synthesis monitored overtime following the addition of 227 G418. While a significant increase in NV viral RNA levels was seen in WT U2OS 228 cells, those lacking G3BP1 were completely unable to support NV RNA synthesis 229 ( Fig 5C) . These data indicate that like for MNV, G3BP1 is essential for human 230.....
Document: VPg-linked RNA, and RNA synthesis monitored overtime following the addition of 227 G418. While a significant increase in NV viral RNA levels was seen in WT U2OS 228 cells, those lacking G3BP1 were completely unable to support NV RNA synthesis 229 ( Fig 5C) . These data indicate that like for MNV, G3BP1 is essential for human 230
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