Author: Yadi Zhou; Yuan Hou; Jiayu Shen; Yin Huang; William Martin; Feixiong Cheng
Title: Network-based Drug Repurposing for Human Coronavirus Document date: 2020_2_5
ID: b4mdiont_65
Snippet: In total, we collected DNA sequences and protein sequences for 15 HCoVs, including three most recent 2019-nCoV genomes, from the NCBI GenBank database (January 28, 2019, Supplementary Table S1). Whole genome alignment and protein sequence identity calculation were performed by Multiple Sequence Alignment in EMBL-EBI database with default parameters. The neighbor joining (NJ) tree was computed from the pairwise phylogenetic distance matrix using M.....
Document: In total, we collected DNA sequences and protein sequences for 15 HCoVs, including three most recent 2019-nCoV genomes, from the NCBI GenBank database (January 28, 2019, Supplementary Table S1). Whole genome alignment and protein sequence identity calculation were performed by Multiple Sequence Alignment in EMBL-EBI database with default parameters. The neighbor joining (NJ) tree was computed from the pairwise phylogenetic distance matrix using MEGA X [77] with 1000 bootstrap replicates. The protein alignment and phylogenetic tree of HCoVs were constructed by MEGA X.
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