Selected article for: "early phase and high level"

Author: Banjar, Ayman; Al-Tawfiq, Jaffar A.; Alruwaily, Amaal; Alserehi, Haleema; Al-Qunaibet, Ada; Alaswad, Rehab; Almutlaq, Hind; Almudaiheem, Abdullah; Khojah, Abdullah T.; Alsaif, Faisal; Almolad, Shaza Karim; Alqahtani, Saeed; AlJurayyan, Abdullah; Alotaibi, Abdullah; Almalki, Safar; Abuhaimed, Yousef; Alkhashan, Abdullah; Alfaifi, Amal; Alabdulkareem, Khaled; Jokhdar, Hani; Assiri, Abdullah; Almudarra, Sami
Title: Seroprevalence of antibodies to SARS-CoV-2 among blood donors in the early month of the pandemic in Saudi Arabia
  • Cord-id: ge4o3svb
  • Document date: 2021_1_16
  • ID: ge4o3svb
    Snippet: BACKGROUND: Serologic testing provides better understanding of SARS-CoV-2 prevalence and its transmission. This study is the first investigation of the prevalence of antibodies to SARS-CoV-2 among blood donors in Saudi Arabia. OBJECTIVE: To estimate the seroprevalence of anti-SARS-CoV-2 antibodies among blood donors in Saudi Arabia during the early phase of the current pandemic. METHODS: Serology results and epidemiological data were analyzed for 837 adult blood donors, with no confirmed SARS-Co
    Document: BACKGROUND: Serologic testing provides better understanding of SARS-CoV-2 prevalence and its transmission. This study is the first investigation of the prevalence of antibodies to SARS-CoV-2 among blood donors in Saudi Arabia. OBJECTIVE: To estimate the seroprevalence of anti-SARS-CoV-2 antibodies among blood donors in Saudi Arabia during the early phase of the current pandemic. METHODS: Serology results and epidemiological data were analyzed for 837 adult blood donors, with no confirmed SARS-CoV-2 infection, in Saudi Arabia from 20 to 25 May 2020. Seroprevalence was determined using electrochemical immunoassay for detecting anti-SARS-CoV-2 antibodies. RESULTS: The overall seroprevalence of anti-SARS-CoV-2 antibodies was 1.4% (12/837). Non-citizens had higher prevalence compared to citizens (odds ratio 13.6, p = 0.001). Having a secondary education as the highest level of education was also significantly associated with high seroprevalence compared to higher education (odds ratio 6.8, p = 0.005). The data showed that the highest seroprevalence was in Makkah (8.1%), Madinah (4.1% with an OR of 0.48 (95% CI: 0.12-1.94), Jeddah (2.3%; OR 0.27; 95%CI: 0.31-2.25), and Qassim (2.9 %, OR: 0.34; 95%CI: 0.04-2.89) and these were not statistically different from the seroprevalence in Makkah region. CONCLUSIONS: At the early stage of the pandemic in Saudi Arabia, the seroprevalence of antibodies to SARS-CoV-2 among blood donors was low but was higher among non-citizens These findings showed that non-citizens and the less educated may be less attentive to preventive measures. Monitoring seroprevalence trend over time require repeated sampling.

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