Selected article for: "particle image and refinement uniform"
Author: Ali Punjani; Haowei Zhang; David J. Fleet
Title: Non-uniform refinement: Adaptive regularization improves single particle cryo-EM reconstruction
  • Document date: 2019_12_16
    • ID: bqwmx5dy_37
    Snippet: . CC-BY-NC-ND 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2019.12.15.877092 doi: bioRxiv preprint ized according to cross-validation. The lipid nanodisc is smoothed while protein structure is maximally retained, leading to improved particle alignments. The change in particle image alignments between uniform and non-unifo.....
    Document: . CC-BY-NC-ND 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2019.12.15.877092 doi: bioRxiv preprint ized according to cross-validation. The lipid nanodisc is smoothed while protein structure is maximally retained, leading to improved particle alignments. The change in particle image alignments between uniform and non-uniform refinement is shown in Figure 3B . The pose changes are particularly large, with most particles changing by more than 3 degrees. This change leads directly to improved structure quality.

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