Selected article for: "Lesion volume and multiple comparison correction"
Author: Brielle C Stark; Alexandra Basilakos; Gregory Hickok; Chris Rorden; Leonardo Bonilha; Julius Fridriksson
Title: Neural organization of speech production: A lesion-based study of error patterns in connected speech
  • Document date: 2019_2_8
    • ID: nzv96tjh_58
    Snippet: The PNT task group did not show significant correlations between paraphasia proportions and apraxia of speech severity (all r < |.36|, all p>0.05). There were no significant correlations between any paraphasia type and age or months post-stroke (all r<|.28|, all p>0.05). Lesion volume significantly correlated with verbal paraphasias (semantically related, r=.34; unrelated=.41; all p<0.05 after multiple comparison correction) but not sound parapha.....
    Document: The PNT task group did not show significant correlations between paraphasia proportions and apraxia of speech severity (all r < |.36|, all p>0.05). There were no significant correlations between any paraphasia type and age or months post-stroke (all r<|.28|, all p>0.05). Lesion volume significantly correlated with verbal paraphasias (semantically related, r=.34; unrelated=.41; all p<0.05 after multiple comparison correction) but not sound paraphasias (neologistic, r=.21; phonemic, r=-.05). AQ showed a similar pattern of correlation (neologistic, r=-.44; semantically related, r=-.32; unrelated, r=-.53; all p<0.05 after multiple comparison correction) but did not correlate with phonemic paraphasias (r=-.11). Lesion volume was significantly related to AQ (r=-.67, p<.001). For subsequent VLSM analyses, lesion volume was used as a covariate.

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