Author: William T Gibson; Daniel M Evans; Jianghong An; Steven JM Jones
Title: ACE 2 Coding Variants: A Potential X-linked Risk Factor for COVID-19 Disease Document date: 2020_4_14
ID: 05w8tv8x_26
Snippet: Whether or not these studies can be done in time to affect patient outcomes during the current 325 pandemic, the fact that three pathogenic coronaviruses (SARS-CoV, 36 MERS-CoV 37 and SARS-CoV-326 2 38 ) have emerged in the past two decades, two of which bind and enter via ACE2, augurs that 327 additional coronaviruses that bind to ACE2 are likely to emerge in the future. Thus, knowledge of this 328 specific host-pathogen interaction at the molec.....
Document: Whether or not these studies can be done in time to affect patient outcomes during the current 325 pandemic, the fact that three pathogenic coronaviruses (SARS-CoV, 36 MERS-CoV 37 and SARS-CoV-326 2 38 ) have emerged in the past two decades, two of which bind and enter via ACE2, augurs that 327 additional coronaviruses that bind to ACE2 are likely to emerge in the future. Thus, knowledge of this 328 specific host-pathogen interaction at the molecular level is important to have at this time. The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.05.026633 doi: bioRxiv preprint
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