Author: Tabatabai, Julia; Fakhiri, Julia; Meyburg, Jochen; Linse, Kai-Philipp; Xu, Man; Söderlund-Venermo, Maria; Grimm, Dirk; Schnitzler, Paul
Title: Severe Human Bocavirus 1 Respiratory Tract Infection in an Immunodeficient Child With Fatal Outcome. Cord-id: kmmvoqar Document date: 2019_1_1
ID: kmmvoqar
Snippet: We report a case of lower respiratory tract infection with human bocavirus 1 (HBoV1) in an immunodeficient 6-month-old boy leading to respiratory failure with fatal outcome. Polymerase chain reaction of serum/tracheal secretions revealed exceptionally high HBoV1-DNA levels and immunoassays showed seroconversion indicating an acute primary HBoV1 infection. All assays for other pathogens were negative, strongly suggesting that HBoV1 was the causative agent in this case.
Document: We report a case of lower respiratory tract infection with human bocavirus 1 (HBoV1) in an immunodeficient 6-month-old boy leading to respiratory failure with fatal outcome. Polymerase chain reaction of serum/tracheal secretions revealed exceptionally high HBoV1-DNA levels and immunoassays showed seroconversion indicating an acute primary HBoV1 infection. All assays for other pathogens were negative, strongly suggesting that HBoV1 was the causative agent in this case.
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