Author: Yanpeng Li; Emilia Gordon; Amanda Idle; Eda Altan; M. Alexis Seguin; Marko Estrada; Xutao Deng; Eric Delwart
Title: Multiple known and a novel parvovirus associated with an outbreak of feline diarrhea and vomiting Document date: 2020_3_25
ID: mygo3qx0_15
Snippet: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.03.24.005876 doi: bioRxiv preprint Using metagenomics, we found FeBoV1, 2, and 3 and a novel chaphamaparvovirus we named 311 fechavirus in a large fraction of fecal samples and fechavirus in all vomit samples from sick cats 312 in a multi-facility outbreak. Subsequent PCR testing confirmed the presence of either a bocavirus 313 or fechavirus.....
Document: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.03.24.005876 doi: bioRxiv preprint Using metagenomics, we found FeBoV1, 2, and 3 and a novel chaphamaparvovirus we named 311 fechavirus in a large fraction of fecal samples and fechavirus in all vomit samples from sick cats 312 in a multi-facility outbreak. Subsequent PCR testing confirmed the presence of either a bocavirus 313 or fechavirus or both (n=1 cat #283) of these viruses in all but one of the seventeen sick cats 314 tested (cat #178). The outbreak in shelter 2 predominantly tested positive for FeBoV (7/9 FeBoV 315 +ve and 2/9 fechavirus +ve) while the sick cats in shelter 3 were mainly shedding fechavirus (6/7 316 fechavirus +ve, 2/7 FeBov +ve). Another cat housed in shelter 2 who developed vomiting after 317 sick cats were transferred back from Shelter 3 was also shedding fechavirus as well as a novel 318 dependovirus. The co-detection of these viral genomes indicate that fechavirus may provide the 319 required help for replication-defective dependoviruses. 320 FPV and feline FCV reads were determined to originate from recently inoculated attenuated 321 vaccine strains while other viruses were deemed to be asymptomatic infections, derived from 322 author/funder. All rights reserved. No reuse allowed without permission.
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