Author: Li, Qiubai; Chen, Lei; Li, Qin; He, Wenjuan; Yu, Jianming; Chen, Li; Cao, Yulin; Chen, Wenlan; Di Wu; Dong, Fang; Cai, Liling; Ran, Qijie; Li, Lei; Liu, Qiaomei; Ren, Wenxiang; Gao, Fei; Wang, Hongxiang; Chen, Zhichao; Gale, Robert Peter; Hu, Yu
Title: Cancer increases risk of in-hospital death from COVID-19 in persons <65 years and those not in complete remission Cord-id: lm9teuij Document date: 2020_7_20
ID: lm9teuij
Snippet: The impact of cancer on outcome of persons with coronavirus disease 2019 (COVID-19) after infection with acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is controversial. We studied 1859 subjects with COVID-19 from seven centers in Wuhan, China, 65 of whom had cancer. We found having cancer was an independent risk factor for in-hospital death from COVID-19 in persons <65 years (hazard ratio [HR] = 2.45, 95% confidence interval [CI], 1.04, 5.76; P = 0.041) but not in those ≥65 years (HR =
Document: The impact of cancer on outcome of persons with coronavirus disease 2019 (COVID-19) after infection with acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is controversial. We studied 1859 subjects with COVID-19 from seven centers in Wuhan, China, 65 of whom had cancer. We found having cancer was an independent risk factor for in-hospital death from COVID-19 in persons <65 years (hazard ratio [HR] = 2.45, 95% confidence interval [CI], 1.04, 5.76; P = 0.041) but not in those ≥65 years (HR = 1.12 [0.56, 2.24]; P = 0.740). It was also more common in those not in complete remission. Risks of in-hospital death were similar in subjects with solid cancers and those with hematological cancers. These data may help predict outcomes of persons with cancer and COVID-19.
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