Selected article for: "cc international license and post infection"
Author: Myra Hosmillo; Jia Lu; Michael R. McAllaster; James B. Eaglesham; Xinjie Wang; Edward Emmott; Patricia Domingues; Yasmin Chaudhry; Timothy J Fitzmaurice; Matthew K.H. Tung; Marc Panas; Gerald McInerney; Nicholas Locker; Craig B. Willen; Ian Goodfellow
Title: Noroviruses subvert the core stress granule component G3BP1 to promote viral VPg-dependent translation
  • Document date: 2019_3_8
    • ID: d0q5lhf4_24
    Snippet: Surprisingly, we were able to detect an ~5 fold increase in viral negative sense RNA 280 production at 6 hours post infection of WT cells in the presence of 2CMC, which, 281 . CC-BY-NC 4.0 International license is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It . https://doi.org/10.1101/571455 doi: bioRxiv preprint given that 2CMC was added after the inoculation phase (Fig 8B) ,.....
    Document: Surprisingly, we were able to detect an ~5 fold increase in viral negative sense RNA 280 production at 6 hours post infection of WT cells in the presence of 2CMC, which, 281 . CC-BY-NC 4.0 International license is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. It . https://doi.org/10.1101/571455 doi: bioRxiv preprint given that 2CMC was added after the inoculation phase (Fig 8B) , likely represents 282 the first round of viral negative sense RNA synthesis, confirming the sensitivity of the 283 assay. Addition of 2CMC during the inoculation phase reduced this background 284 levels (data not shown). 285

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