Author: Leili Zhang; David R. Bell; Binquan Luan; Ruhong Zhou
Title: Exploring the Binding Mechanism between Human Profilin (PFN1) and Polyproline-10 through Binding Mode Screening Document date: 2018_9_16
ID: 40pe21lm_6
Snippet: Specifically, we use human profilin (PFN1) and polyproline-10 (P10) as a model system. The PPI pair PFN1-P10 is picked due to its importance and simplicity: P10 is a relatively rigid peptide adopting a polyproline II (PPII) helix 19 that binds to surface aromatic residues of PFN1......
Document: Specifically, we use human profilin (PFN1) and polyproline-10 (P10) as a model system. The PPI pair PFN1-P10 is picked due to its importance and simplicity: P10 is a relatively rigid peptide adopting a polyproline II (PPII) helix 19 that binds to surface aromatic residues of PFN1.
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