Selected article for: "adenine dinucleotide and adp nicotinamide"
Author: Hopp, Ann-Katrin; Hottiger, Michael O.
Title: Uncovering the Invisible: Mono-ADP-ribosylation Moved into the Spotlight
  • Cord-id: lkezb7fw
  • Document date: 2021_3_19
    • ID: lkezb7fw
    Snippet: Adenosine diphosphate (ADP)-ribosylation is a nicotinamide adenine dinucleotide (NAD(+))-dependent post-translational modification that is found on proteins as well as on nucleic acids. While ARTD1/PARP1-mediated poly-ADP-ribosylation has extensively been studied in the past 60 years, comparably little is known about the physiological function of mono-ADP-ribosylation and the enzymes involved in its turnover. Promising technological advances have enabled the development of innovative tools to de
    Document: Adenosine diphosphate (ADP)-ribosylation is a nicotinamide adenine dinucleotide (NAD(+))-dependent post-translational modification that is found on proteins as well as on nucleic acids. While ARTD1/PARP1-mediated poly-ADP-ribosylation has extensively been studied in the past 60 years, comparably little is known about the physiological function of mono-ADP-ribosylation and the enzymes involved in its turnover. Promising technological advances have enabled the development of innovative tools to detect NAD(+) and NAD(+)/NADH (H for hydrogen) ratios as well as ADP-ribosylation. These tools have significantly enhanced our current understanding of how intracellular NAD dynamics contribute to the regulation of ADP-ribosylation as well as to how mono-ADP-ribosylation integrates into various cellular processes. Here, we discuss the recent technological advances, as well as associated new biological findings and concepts.

    Search related documents:
    Co phrase search for related documents
    • active enzyme and adp ribose: 1, 2
    • acute respiratory syndrome coronavirus and adp ribose: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
    • acute respiratory syndrome coronavirus and adp ribose adpr: 1, 2
    • adenine dinucleotide and adp ribose: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16
    • adenine dinucleotide and adp ribose adpr: 1, 2, 3
    • adenine dinucleotide phosphate and adp ribose: 1, 2
    • adenine nucleotide and adp ribose: 1