Selected article for: "clinical relevance and polymerase chain reaction"

Author: de Lima, C.R.A.; Mirandolli, T.B.; Carneiro, L.C.; Tusset, C.; Romer, C.M.; Andreolla, H.F.; Baethgen, L.F.; Pasqualotto, A.C.
Title: Prolonged respiratory viral shedding in transplant patients
  • Cord-id: luiilr5z
  • Document date: 2013_12_2
  • ID: luiilr5z
    Snippet: Respiratory viral infections are frequent causes of morbidity in transplant patients. We screened symptomatic adult transplant recipients for respiratory viruses in a cohort of patients attending a referral medical center in Brazil. The duration of viral shedding and the prevalence of viral codetections were also determined. During a 1‐year period (2011–2012), swabs were obtained from 50 patients. An in‐house polymerase chain reaction panel designed to detect 10 viruses was used. Viruses w
    Document: Respiratory viral infections are frequent causes of morbidity in transplant patients. We screened symptomatic adult transplant recipients for respiratory viruses in a cohort of patients attending a referral medical center in Brazil. The duration of viral shedding and the prevalence of viral codetections were also determined. During a 1‐year period (2011–2012), swabs were obtained from 50 patients. An in‐house polymerase chain reaction panel designed to detect 10 viruses was used. Viruses were identified in 19 (38%) patients, particularly parainfluenza III (32%) and the respiratory syncytial virus (20%); multiple viruses were identified in 26% of patients. Prolonged viral shedding was observed with 60% of individuals excreting viruses for >10 days. The clinical and epidemiologic relevance of prolonged viral shedding remains to be determined.

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