Author: Felix Grünberger; Robert Knüppel; Michael Jüttner; Martin Fenk; Andreas Borst; Robert Reichelt; Winfried Hausner; Jörg Soppa; Sebastien Ferreira-Cerca; Dina Grohmann
Title: Nanopore-based native RNA sequencing provides insights into prokaryotic transcription, operon structures, rRNA maturation and modifications Document date: 2019_12_19
ID: e5p4metz_56
Snippet: The situation is different for Pyrococcus: Native Nanopore data suggest that the rRNA is heavily 631 modified. However, the number, exact positions and chemical identity of these modifications are 632 currently unknown. Hence, an analysis of how often base modifications lead to wrongly identified 633 nucleotides in the 16S rRNA sequence cannot be performed ( Supplementary Fig. 16c,g) . 634 635 636 the author/funder. All rights reserved. No reuse .....
Document: The situation is different for Pyrococcus: Native Nanopore data suggest that the rRNA is heavily 631 modified. However, the number, exact positions and chemical identity of these modifications are 632 currently unknown. Hence, an analysis of how often base modifications lead to wrongly identified 633 nucleotides in the 16S rRNA sequence cannot be performed ( Supplementary Fig. 16c,g) . 634 635 636 the author/funder. All rights reserved. No reuse allowed without permission.
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