Author: Yuri I. Wolf; Darius Kazlauskas; Jaime Iranzo; Adriana LucÍa-Sanz; Jens H. Kuhn; Mart Krupovic; Valerian V. Dolja; Eugene V. Koonin
Title: Origins and Evolution of the Global RNA Virome Document date: 2018_10_24
ID: 8z78shbf_20
Snippet: The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. virus genes (or proteins and domains, for simplicity), both formally, using the ML-based Gloome 284 method (51), and informally, from parsimony considerations. 285 These reconstructions reveal a high level of branch-specificity in the evolution of the gene 286 repertoire of RNA viruses. The only protein that is likely to have been gained at the base of the .....
Document: The copyright holder for this preprint (which was not peer-reviewed) is the author/funder. virus genes (or proteins and domains, for simplicity), both formally, using the ML-based Gloome 284 method (51), and informally, from parsimony considerations. 285 These reconstructions reveal a high level of branch-specificity in the evolution of the gene 286 repertoire of RNA viruses. The only protein that is likely to have been gained at the base of the 287 eukaryotic virus subtree (Branches 2 to 5) (that also includes the bacterial cystoviruses) is the 288 single jelly-roll capsid protein (SJR-CP) ( Figure S2A ). Retroelements lack capsid proteins, and 289 therefore, there is no indication that SJR-CP was present in the hypothetical element that with gene gain-loss reconstruction suggests the following evolutionary scenario for Branch 1 296 All rights reserved. No reuse allowed without permission.
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