A Case of Multiple Cerebral Infarction Associated with Cerebral Vasculitis in a Patient with Ulcerative Colitis.

Yasuda, Takeshi; Takagi, Tomohisa; Hasegawa, Daisuke; Hirose, Ryohei; Inoue, Ken; Dohi, Osamu; Yoshida, Naohisa; Kamada, Kazuhiro; Uchiyama, Kazuhiko; Ishikawa, Takeshi; Konishi, Hideyuki; Naito, Yuji; Itoh, Yoshito

A 40-year-old man was admitted to the hospital due to both a worsening of symptoms associated with ulcerative colitis (UC), which had been diagnosed 3 years previously, and limb paralysis. Colonoscopy revealed severe pancolitis-type UC. He was diagnosed with cerebral vasculitis with multiple white matter infarctions associated with the disease activity of UC by contrast-enhanced head magnetic resonance imaging. Mesalazine at 4,000 mg/day and prednisolone at 60 mg/day were started, and the prednisolone dosage was thereafter gradually reduced and switched to golimumab. He achieved a long-term remission from UC, and thereafter his neurological abnormalities improved significantly. He had no recurrence of cerebral infarction.