Author: Blach, S; Blomé, M; Duberg, Aâ€S; Jerkeman, A; KÃ¥berg, M; Klasa, Pâ€E; Lagging, M; Razaviâ€Shearer, D; Razavi, H; Aleman, S
Title: Hepatitis C Elimination in Sweden: Progress, Challenges and Opportunities for Growth in the time of COVIDâ€19 Cord-id: rxp5qxwe Document date: 2021_5_29
ID: rxp5qxwe
Snippet: BACKGROUND & AIMS: In 2014, the burden of hepatitis C virus (HCV) in Sweden was evaluated, to establish a baseline and inform public health interventions. Considering the changing landscape of HCV treatment, prevention, and care, and in light of the COVIDâ€19 pandemic, this analysis seeks to evaluate Sweden’s progress toward the WHO elimination targets and identify remaining barriers. METHODS: The data used for modeling HCV transmission and disease burden in Sweden were obtained through liter
Document: BACKGROUND & AIMS: In 2014, the burden of hepatitis C virus (HCV) in Sweden was evaluated, to establish a baseline and inform public health interventions. Considering the changing landscape of HCV treatment, prevention, and care, and in light of the COVIDâ€19 pandemic, this analysis seeks to evaluate Sweden’s progress toward the WHO elimination targets and identify remaining barriers. METHODS: The data used for modeling HCV transmission and disease burden in Sweden were obtained through literature review, unpublished sources, and expert input. A dynamic Markov model was employed to forecast population sizes and incidence of HCV through 2030. Two scenarios (“2019 Base†and “WHO Targetsâ€) were developed to evaluate Sweden’s progress toward HCV elimination. RESULTS: At the beginning of 2019, there were 29,700 (95% UI: 19,300 – 33,700) viremic infections in Sweden. Under the base scenario, Sweden would achieve and exceed the WHO targets for diagnosis, treatment, and liverâ€related death. However, new infections would decrease by less than 10%, relative to 2015. Achieving all WHO targets by 2030 would require 1) expanding harm reduction programs to reach more than 90% of PWID and 2) treating 90% of HCV+ PWID engaged in harm reduction programs and ≥7% of PWID not involved in harm reduction programs, annually by 2025. CONCLUSIONS: It is of utmost importance that Sweden, and all countries, find sustainability in HCV programs by broadening the setting and base of providers to provide stability and continuity of care during turbulent times.
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