Pustular psoriasis flare-up in a patient with COVID-19

Miladi, Ronak; Janbakhsh, Alireza; Babazadeh, Arefeh; Aryanian, Zeinab; Ebrahimpour, Soheil; Barary, Mohammad; Sio, Terence T; Wollina, Uwe; Goldust, Mohamad; Mohseni Afshar, Zeinab

INTRODUCTION: The various cutaneous manifestations have lately appeared in the setting of COVID-19. Psoriasis flare-ups have been reported during a COVID-19 infection. CASE PRESENTATION: We present a case of a 32-year-old woman with COVID-19 who presented with generalized pustular psoriasis. She received oral prednisolone, hydroxyzine, and topical clobetasol. The patient received follow-up two weeks later and found that her lesions were favorably desquamating. METHODS: The PubMed, SCOPUS, and ISI Web of Science databases were thoroughly searched for English studies reporting psoriasis flare-ups following SARS-CoV-2 infection. Ten case reports/series were included after screening. CONCLUSIONS: Our case report brings awareness to clinicians for the possible cutaneous manifestation of COVID-19, which should be considered part of the differential diagnoses.