Selected article for: "false negative and respiratory tract"
Author: Jing-Wen Ai; Hao-Cheng Zhang; Teng Xu; Jing Wu; Mengqi Zhu; Yi-Qi Yu; Han-Yue Zhang; Zhongliang Shen; Yang Li; Xian Zhou; Guo-Qing Zang; Jie Xu; Wen-Jing Chen; Yong-Jun Li; De-Sheng Xie; Ming-Zhe Zhou; Jing-Ying Sun; Jia-Zhen Chen; Wen-Hong Zhang
Title: Optimizing diagnostic strategy for novel coronavirus pneumonia, a multi-center study in Eastern China
  • Document date: 2020_2_17
    • ID: nqxo3f45_22
    Snippet: In the laboratory-confirmed NCP cases, 15% of the nasopharyngeal swab specimens were negative for RT-PCR on the first time and turned to positive on the second time, while another 15% of the specimens tested negative both time and was finally diagnosed through metagenomics sequencing. The result suggested that the current RT-PCR for SARS-COV-2 indeed had at least 15% of false negative rate. However, these 3 mNGS positive but RT-PCR negative sampl.....
    Document: In the laboratory-confirmed NCP cases, 15% of the nasopharyngeal swab specimens were negative for RT-PCR on the first time and turned to positive on the second time, while another 15% of the specimens tested negative both time and was finally diagnosed through metagenomics sequencing. The result suggested that the current RT-PCR for SARS-COV-2 indeed had at least 15% of false negative rate. However, these 3 mNGS positive but RT-PCR negative samples had a relatively low sequences reads, which suggested low viral loads in the upper respiratory tract and the possibility low contagious risk for these patients.

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